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@unpublished{sherrell:medsi2020-wepc15,
author = {D.A. Sherrell},
title = {{Nylon Mesh Holder for Serial Crystallography Experiments}},
booktitle = {Proc. MEDSI'20},
language = {english},
intype = {presented at the},
series = {Mechanical Engineering Design of Synchrotron Radiation Equipment and Instrumentation},
number = {11},
venue = {Chicago, IL, USA},
publisher = {JACoW Publishing, Geneva, Switzerland},
month = {10},
year = {2021},
note = {presented at MEDSI'20 in Chicago, IL, USA, unpublished},
abstract = {{Over the last two years, we have developed a 3D printed nylon mesh holder for serial synchrotron crystallography (SSX) experiments. We are moving away from the complications in some devices to a cheap, easy, and user-friendly format. The device uses a new, patented*, two-layer (one rigid and one flexible) substrate technique developed at Argonne. The SSX device and method, which incorporates a modular high-performance computing data analysis backend, was used to demonstrate never-before-seen molecular dynamics** and discovered the methylated form of the SARS-CoV-2 Nsp10/16 protein*** complex. Named ALEX (Advanced Lightweight Encapsulation for Crystallography) for short, we are actively using, upgrading, and reaching out to collaborators. We are using ALEX for serial experiments at APS but feel the design might be useful for other applications.}},
}